PT - JOURNAL ARTICLE AU - AlMohammedi, Renad M. AU - AlMutairi, Hadeel AU - AlHoussien, Rana O. AU - AlOtayan, Malack T. AU - AlMutairi, Abeer K. AU - Bafail, Wejdan O. AU - Khan, Altaf AU - Khatri, Ismail A. TI - Brainstem hemorrhage is uncommon and is associated with high morbidity, mortality, and prolonged hospitalization AID - 10.17712/nsj.2020.2.20190102 DP - 2020 Apr 01 TA - Neurosciences Journal PG - 91--96 VI - 25 IP - 2 4099 - http://nsj.org.sa/content/25/2/91.short 4100 - http://nsj.org.sa/content/25/2/91.full SO - Neurosciences (Riyadh)2020 Apr 01; 25 AB - Objectives: To determine the frequency, risk factors, and outcomes of patients with brainstem hemorrhage in stroke center at King Abdulaziz Medical City, Riyadh.Methods: A retrospective, observational cohort study including all patients with brainstem hemorrhage from January 2014 to December 2017. The clinical presentation, location of hemorrhage, complications and clinical outcomes were analyzed.Results: Of 1921 stroke patients, 219 had hemorrhagic stroke (11.4%), of whom only 10 (4.6%) had brainstem hemorrhage, comprising 0.5% of all stroke patients. All patients were men; mean age was 58.5 years. Most frequent presenting symptoms were headache (70%), unilateral weakness (60%), and loss of consciousness (50%). All patients had hemorrhage in pons, 5 had concomitant cerebellar hemorrhage (50%), one had medullary hemorrhage, and one midbrain hemorrhage (10% each). Mean ICU stay was 17 days; mean hospital stay was 58 days. At the time of discharge, three (30%) had mRS of 0-2, 5 (50%) had mRS of 3-5, whereas 2 (20%) had died. Glasgow coma scale (GCS) of >8 at presentation was associated with a good outcome at three months (p=0.03). Presentation within six hours of symptom onset (p=0.233), hypertension on presentation (p=0.233), and age less than 60 years (p=0.065) did not affect discharge outcomes.Conclusion: Brainstem hemorrhage occurred in 0.5% of all stroke patients. It was associated with high morbidity and mortality. Low Glasgow Coma Scale at presentation was associated with poor outcomes.