Summary
Three cases of brain abscesses caused by Ramichloridium obovoideum are reported. Inspite of adequate antifungal chemotherapy and multiple surgical procedures, all the three patients died of the rupture of a recurrant abscess into the ventricles. Ramichloridium obovoideum was identified as the causative fungus of these brain abscesses. Clinical, histological and mycological features of these cases are described. To our knowledge this is the first time that this fungus is isolated from a brain abscess in Saudi Arabia. The possibility that this life threatening cerebral mycosis may be endemic in this part of the world is considered.
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References
Ajello L (1975) Phaeohyphomycosis: definition and etiology. In: Mycosis. Pan Am Health Organization, Scientific publication No 304, Washington, D.C., pp 126–133
Block ER, Jennings AE, Bennett JE (1973) Experimental therapy of cladosporiosis and sporotrichosis with 5-fluorocytosine. Antimicrob Agent Chemother, pp 95–98
Fetter BF, Klintworth GK, Hendry WS (1967) Mycosis of the central nervous system. The Williams & Wilkins Company, Baltimore
Fukushiro R, Kagana S, Nishiyama S, Takahashi H (1957) Un cas de chromoblastomycose cutaneé avec metastase cérébrale mortelle. Presse Medicale 75: 2142–2143
Fuste FJ, Ajello L, Threlkeld R, Henry Jr JE (1973) Drechslera hawaiiensis: Causative agent of a fatal fungal meningo-encephalitis. Sabouraudia 11: 59–63
Hart PD, Russel E, Remington JS (1969) The compromised host and infection. Il Deep fungal infection. J Infectious Diseases 120: 169–191
Lucasse C, Chardome J, Magis P, Vanbreuseghem R (1954) Mycose cérébrale par Cladosporum trichoides chez un Indigéne du congo Belge. Annales de la Société Belge de Médecine Tropical 34: 375–84
Middleton FG, Jurgenson PF, Utz JP, Shadomy S, Shadomy JH (1976) Brain abscess caused by Cladosporium trichoides. Arch Intern Med 136: 444–448
Seaworth BJ, Kwon-Chung KH, Hemilton JD, Perfect JR (1983) Brain abscess caused by a variety of Cladosporium Trichoides. Am J Clin Pathol 79: 747–752
Shadomy S (1969) In vitro studies with 5-fluorocytosine. Appl Microbiol 17: 871–877
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Naim-ur-Rahman, Mahgoub, E.S. & Chagla, A.H. Fatal brain abscesses caused by Ramichloridium obovoideum: Report of three cases. Acta neurochir 93, 92–95 (1988). https://doi.org/10.1007/BF01402887
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DOI: https://doi.org/10.1007/BF01402887