Sleep quality, daytime sleepiness, and insomnia in patient with epilepsy: A single center experience from Saudi Arabia
AA Alenizi, AM Eskandrani, SA Asiri… - Neurosciences …, 2023 - nsj.org.sa
Objectives: To measure the burden of insomnia and daytime sleepiness (DTS) and their
effects on sleep quality, and the risk factors of poor quality of sleep. Methods: We conducted a …
effects on sleep quality, and the risk factors of poor quality of sleep. Methods: We conducted a …
[HTML][HTML] KCNMA1-related refractory status epilepticus responding to vagal nerve stimulation: Case report and literature review
AA Al-Attas, AY Aldayel, AM Eskandrani… - Neurosciences Journal, 2022 - nsj.org.sa
Epilepsy, one of the most prevalent chronic neurological diseases, can cause severe morbidity
as well as mortality. A mutation of the KCNMA1 gene results in a rare genetic disease …
as well as mortality. A mutation of the KCNMA1 gene results in a rare genetic disease …
Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis
…, MM Alanazi, AJ Obaidullah, RO Eskandrani… - Bioorganic …, 2020 - Elsevier
The in vitro cytotoxicity of some substituted quinazolinones, 1–15, was evaluated using NCI (10
µM) in a full NCI 59–cell line panel assay. Relative to the reference drug, imatinib (PCE = …
µM) in a full NCI 59–cell line panel assay. Relative to the reference drug, imatinib (PCE = …
[HTML][HTML] Targeting Transcriptional CDKs 7, 8, and 9 with Anilinopyrimidine Derivatives as Anticancer Agents: Design, Synthesis, Biological Evaluation and In Silico …
R Eskandrani, LS Al-Rasheed, SA Ansari, AH Bakheit… - Molecules, 2023 - mdpi.com
Cyclin-dependent kinases (CDKs) are promising targets in chemotherapy. In this study, we
report a series of 2-anilinopyrimidine derivatives with CDK inhibitory activity. Twenty-one …
report a series of 2-anilinopyrimidine derivatives with CDK inhibitory activity. Twenty-one …
[PDF][PDF] A comparative study to find out the aesthetic relationship between facial and dental parameters in Saudi population
…, AM AlGhamdi, RM Eskandrani - Int J Dent …, 2019 - article.dentalsciencesresearch.com
… for measuring the BZ was that facial width is taken between the most lateral points on the
external surfaces of the zygomatic arches, for measuring the IA the external width of the ala of …
external surfaces of the zygomatic arches, for measuring the IA the external width of the ala of …
Synthesis, antitumor, and apoptosis-inducing activities of novel 5-arylidenethiazolidine-2, 4-dione derivatives: histone deacetylases inhibitory activity and molecular …
… The mass spectra of our final targets displayed the correct molecular ion peaks (M + or M +
+… On the other hand, the percentage of cells in the S and G2/M phases decreased significantly …
+… On the other hand, the percentage of cells in the S and G2/M phases decreased significantly …
Design, synthesis, antitumor, and VEGFR-2 inhibition activities of novel 4-anilino-2-vinyl-quinazolines: Molecular modeling studies
The antitumor activity of newly synthesized 4-anilino-2-vinylquinazolines 8a-r was measured
comparable to sorafenib as a standard drug. The 2-vinylquinazolines 8a-r were evaluated …
comparable to sorafenib as a standard drug. The 2-vinylquinazolines 8a-r were evaluated …
Recessive AFG3L2 mutation causes progressive microcephaly, early onset seizures, spasticity, and basal ganglia involvement
A Eskandrani, A AlHashem, ES Ali, S AlShahwan… - Pediatric Neurology, 2017 - Elsevier
Background Mutations in AFG3L2, a gene encoding a subunit of the mitochondrion m-AAA
protease, cause spinocerebellar ataxia type 28 and recessive spastic ataxia type 5. …
protease, cause spinocerebellar ataxia type 28 and recessive spastic ataxia type 5. …
[HTML][HTML] Design, synthesis, and carbonic anhydrase inhibition activities of Schiff bases incorporating benzenesulfonamide scaffold: Molecular docking application
In this study, The inhibitory actions of human carbonic anhydrase (CA, EC 4.2.1.1) (hCA)
isoforms I, II, IX, and XII are being examined using recently synthesized substituted hydroxyl …
isoforms I, II, IX, and XII are being examined using recently synthesized substituted hydroxyl …
[HTML][HTML] Synthesis of novel spirochromane incorporating Schiff's bases, potential antiproliferative activity, and dual EGFR/HER2 inhibition: Cell cycle analysis and in …
Spirochromanes incorporating Schiff's bases and semicarbazones 4a-e and 5a-j were
synthesizedand analyzed for their potential antiproliferative activity using four human cancer cell …
synthesizedand analyzed for their potential antiproliferative activity using four human cancer cell …