<p id="p001">Early-onset, severe retinal dystrophy caused by mutations in the gene encoding
retinal pigment epithelium–specific 65-kD protein (<italic>RPE65</italic>) is associated …

Sex differences in human behavior show adaptive complementarity: Males have better motor
and spatial abilities, whereas females have superior memory and social cognition skills. …

The human MDR1 P-glycoprotein (Pgp) extrudes a variety of drugs across the plasma
membrane. The homologous MDR3 Pgp is required for phosphatidylcholine secretion into bile. …

The impact of generative artificial intelligence (AI) on medical publishing practices is currently
unknown. However, as our experiences underline, generative AI could have substantial …

Context To better target services to those who may benefit, many guidelines recommend
incorporating life expectancy into clinical decisions. Objective To assess the quality and …

To assess quantitatively the association between benzene exposure and leukemia, we
examined the mortality rate of a cohort with occupational exposure to benzene. Cumulative …

The human multidrug-resistance protein (MRP) gene family contains at least six members:
MRP1, encoding the multidrug-resistance protein; MRP2 or cMOAT, encoding the canalicular …

Background Mutations in RPE65 cause Leber’s congenital amaurosis, a progressive retinal
degenerative disease that severely impairs sight in children. Gene therapy can result in …

BACKGROUND/OBJECTIVES Physical distancing during the COVID‐19 pandemic may have
unintended, detrimental effects on social isolation and loneliness among older adults. Our …

Retroviral and lentiviral vector integration into host-cell chromosomes carries with it a finite
chance of causing insertional mutagenesis 1 . This risk has been highlighted by the induction …