User profiles for Hasan M. Aytac

Hasan Mervan Aytac

Basaksehir Cam and Sakura City Hospital
Verified email at saglik.gov.tr
Cited by 178

[HTML][HTML] Investigation of inflammation related gene polymorphism of the mannose-binding lectin 2 in schizophrenia and bipolar disorder

HM Aytac, MS Yazar, A Erol, S Pehlivan - Neurosciences Journal, 2021 - nsj.org.sa
Objectives: To investigate the association between mannose-binding lectin 2 (MBL2) codon
54 polymorphism and clinical features of patients diagnosed with schizophrenia (SCZ) or …

[HTML][HTML] Association of intron 4 VNTR polymorphism in the NOS3 gene with rapid cycling and treatment resistance in bipolar disorder: a case-control study

HM Aytac, M Pehlivan, Y Oyaci, S Pehlivan - Neurosciences Journal, 2022 - nsj.org.sa
Objective: To evaluate the relationship between patients’ clinical parameters, especially
clinical specifiers, and the intron 4 VNTR variant of the endothelial nitric oxide synthase (NOS3) …

Tumor necrosis factor-alpha (TNF-α)− 238 G/A polymorphism is associated with the treatment resistance and attempted suicide in schizophrenia

HM Aytac, K Ozdilli, FC Tuncel, M Pehlivan… - Immunological …, 2022 - Taylor & Francis
Abnormality of the immune system may play an important role in the pathogenesis of
schizophrenia (SCZ). We aim to investigate the relationship between clinical features of SCZ and …

Evaluation of COMT (rs4680), CNR2 (rs2501432), CNR2 (rs2229579), UCP2 (rs659366), and IL-17 (rs763780) gene variants in synthetic cannabinoid use disorder …

…, HM Aytac, S Kurnaz, M Pehlivan… - Journal of addictive …, 2020 - Taylor & Francis
Synthetic cannabinoids (SC) are psychoactive drugs that generally produce more severe
clinical outcomes compared to Δ9-tetrahydrocannabinol. This study aimed to evaluate the …

Association of MIF and MBL2 gene polymorphisms with attempted suicide in patients diagnosed with schizophrenia or bipolar disorder

HM Aytac, Y Oyaci, MS Yazar, A Erol… - Journal of clinical …, 2020 - Elsevier
The aim of this study to investigate the genetic polymorphisms in macrophage inhibitory
factor (MIF) and mannose-binding lectin 2 (MBL2) gene in schizophrenia (SCZ) or bipolar …

Genetic polymorphism of IL-17F rs763780 contributes to the susceptibility to bipolar disorder but not to schizophrenia in the Turkish population

Y Oyaci, HM Aytac, M Pehlivan… - … , Nucleotides & Nucleic …, 2023 - Taylor & Francis
This study aims to investigate the genetic polymorphism in the interleukin-17F (IL-17F) (rs763780,
7488 A/G) gene in bipolar disorder (BD) and schizophrenia (SCZ) patients by …

Quantitative detection of methylated SOCS-1 in schizophrenia and bipolar disorder considering SOCS-1 -1478CA/del polymorphism and clinical parameters

HM Aytac, S Pehlivan, M Pehlivan, Y Oyaci - Irish Journal of Medical …, 2023 - Springer
Background We aimed to investigate the quantitative detection of methylated suppressor of
cytokine signaling-1 (SOCS-1) in schizophrenia (SCZ) and bipolar disorder (BD), …

Detection of altered methylation of MB-COMT promotor and DRD2 gene in cannabinoid or synthetic cannabinoid use disorder regarding gene variants and clinical …

Y Oyaci, HM Aytac, O Pasin… - Journal of addictive …, 2021 - Taylor & Francis
This study aims to investigate the association between cannabinoid use disorder (CUD) or
synthetic cannabinoid use disorder (SCUD) and methylation status of MB-COMT (membrane-…

[HTML][HTML] DNA methylation pattern of gene promoters of MB-COMT, DRD2, and NR3C1 in Turkish patients diagnosed with schizophrenia

HM Aytac, Y Oyaci, M Pehlivan… - Clinical …, 2022 - ncbi.nlm.nih.gov
… : Hasan Mervan Aytac and Sacide Pehlivan. Conceived and designed the study: Hasan
Mervan Aytac, … Acquired, analyzed, and interpreted all data: Hasan Mervan Aytac and Mustafa …

Macrophage migration inhibitory factor-173 G/C polymorphism is associated with the age of onset and insight in Schizophrenia in the Turkish population

HM Aytac, Y Oyaci, MS Yazar, S Pehlivan - Neurological Research, 2021 - Taylor & Francis
Objective To evaluate the genetic variant in the macrophage migration inhibitory factor (MIF)
−173 G/C in patients with schizophrenia (SCZ) by comparing genotype distributions of MIF −…