Inflammation is a natural protective mechanism that occurs when the body’s tissue homeostatic
mechanisms are disrupted by biotic, physical, or chemical agents. The immune response …

An essential target for COVID-19 is the main protease of SARS-CoV-2 (Mpro). With the
objective of targeting this receptor, a novel set of pyrido[1,2-a]pyrrolo[2,3-d]pyrimidines with …

Over the last decade, researchers have discovered that a group of apparently unrelated
neurodegenerative disorders, such as Parkinson's disease, have remarkable cellular and …

Abnormal mitochondrial morphology and metabolic dysfunction have been observed in
many neurodegenerative disorders (NDDs). Mitochondrial dysfunction can be caused by …

We determined various forces involved in shaping codon usage of the genes linked to brain
iron accumulation and infantile neuroaxonal dystrophy. The analysis paved the way for …

Glioblastoma multiforme, a rare traumatic brain disorder, is at the research climax for its
uncontrolled growth leading to a catastrophic outcome. Throwing light on the target-based virtual …

The pathogenesis of pulmonary fibrosis (PF) is extremely complex and involves numerous
intersecting pathways. The successful management of PF may require combining multiple …

Avicennia alba is a mangrove plant that is extensively used to treat severe health issues.
This focus of this study was to investigate the antidiabetic, anti-inflammatory, analgesic, and …

DJ-1 is a multifunctional protein affecting different biological and cellular processes. In
addition, DJ-1 has roles in regulating mitochondrial function. Loss-of-function mutations in DJ-1 …

Parkinson’s disease (PD) is a progressive widespread neurodegenerative disorder affecting
the brain. It is characterized by dopaminergic neuron degeneration in the substantia nigra …