cDNA microarrays are capable of profiling gene expression patterns of tens of thousands of
genes in a single experiment. DNA targets, in the form of 3 expressed sequence tags (ESTs), …

Background The androgen-receptor isoform encoded by splice variant 7 lacks the ligand-binding
domain, which is the target of enzalutamide and abiraterone, but remains constitutively …

Background Many cases of hereditary breast cancer are due to mutations in either the
BRCA1 or the BRCA2 gene. The histopathological changes in these cancers are often …

The most common human cancers are malignant neoplasms of the skin 1 , 2 . Incidence of
cutaneous melanoma is rising especially steeply, with minimal progress in non-surgical …

Gene expression can be quantitatively analyzed by hybridizing fluor-tagged mRNA to targets
on a cDNA microarray. Comparison of gene expression levels arising from cohybridized …

Hepatocellular carcinoma (HCC) is one of the most common and aggressive human
malignancies. Its high mortality rate is mainly a result of intra-hepatic metastases. We analyzed the …

Background Hepatocellular carcinoma is a common and aggressive cancer that occurs mainly
in men. We examined microRNA expression patterns, survival, and response to interferon …

Hepatocellular carcinoma (HCC) is an aggressive malignancy mainly due to metastases or
postsurgical recurrence. We postulate that metastases are influenced by the liver …

The heterogeneous nature of hepatocellular carcinoma (HCC) and the lack of appropriate
biomarkers have hampered patient prognosis and treatment stratification. Recently, we have …

To investigate the phenotype associated with estrogen receptor α (ER) expression in breast
carcinoma, gene expression profiles of 58 node-negative breast carcinomas discordant for …