[HTML][HTML] Treatment-Resistant Schizophrenia, Clozapine Resistance, Genetic Associations, and Implications for Precision Psychiatry: A Scoping Review
J Ying, QH Chew, RS McIntyre, K Sim - Genes, 2023 - mdpi.com
Treatment-resistant schizophrenia (TRS) is often associated with severe burden of disease,
poor quality of life and functional impairment. Clozapine is the gold standard for the …
poor quality of life and functional impairment. Clozapine is the gold standard for the …
Genetic polymorphism of IL-17F rs763780 contributes to the susceptibility to bipolar disorder but not to schizophrenia in the Turkish population
This study aims to investigate the genetic polymorphism in the interleukin-17F (IL-
17F)(rs763780, 7488 A/G) gene in bipolar disorder (BD) and schizophrenia (SCZ) patients …
17F)(rs763780, 7488 A/G) gene in bipolar disorder (BD) and schizophrenia (SCZ) patients …
Quantitative detection of methylated SOCS-1 in schizophrenia and bipolar disorder considering SOCS-1 -1478CA/del polymorphism and clinical parameters
Background We aimed to investigate the quantitative detection of methylated suppressor of
cytokine signaling-1 (SOCS-1) in schizophrenia (SCZ) and bipolar disorder (BD) …
cytokine signaling-1 (SOCS-1) in schizophrenia (SCZ) and bipolar disorder (BD) …
[HTML][HTML] Unique genetic architecture of CSF and brain metabolites pinpoints the novel targets for the traits of human wellness
Brain metabolism perturbation can contribute to traits and diseases. We conducted the first
large-scale CSF and brain genome-wide association studies, which identified 219 …
large-scale CSF and brain genome-wide association studies, which identified 219 …
[HTML][HTML] Association of intron 4 VNTR polymorphism in the NOS3 gene with rapid cycling and treatment resistance in bipolar disorder: a case-control study
Objective: To evaluate the relationship between patients' clinical parameters, especially
clinical specifiers, and the intron 4 VNTR variant of the endothelial nitric oxide synthase …
clinical specifiers, and the intron 4 VNTR variant of the endothelial nitric oxide synthase …
[HTML][HTML] Interleukin-1 receptor antagonist (IL-1RA) and interleukin-4 (IL-4) variable number of tandem repeat polymorphisms in schizophrenia and bipolar disorder: an …
Background Pro-inflammatory/anti-inflammatory cytokine imbalance in cerebrospinal fluid or
plasma of schizophrenia (SCZ) and bipolar disorder (BD) patients has been documented …
plasma of schizophrenia (SCZ) and bipolar disorder (BD) patients has been documented …
IL2RA rs2104286 and IL2 rs2069762 polymorphisms may be associated with bipolar disorder and its clinical findings
Study results supported that immuno-inflammatory pathways in the brain and environment
contribute to the etiopathogenesis of bipolar disorder (BD), a chronic affective disease. Our …
contribute to the etiopathogenesis of bipolar disorder (BD), a chronic affective disease. Our …
[PDF][PDF] Evaluation of Serum Complement Levels and Factors Affecting Treatment Resistance in Patients with Schizophrenia
M Goker, HM Aytac, O Guclu - Psychiatry and …, 2023 - psychiatry-psychopharmacology …
Background: There are increasing investigations about the potential role of the complement
system in disorders affecting the central nervous system, including schizophrenia. Therefore …
system in disorders affecting the central nervous system, including schizophrenia. Therefore …
Evaluation of gene-gene interaction between the interleukin (IL)-2 and IL-2RA gene polymorphisms in schizophrenia patients in the Turkish Population
Objectives: To evaluate the genetic polymorphisms in IL-2 and IL-2RA genes in
schizophrenia (SCZ) patients by comparing them with healthy controls. Methods: A sample …
schizophrenia (SCZ) patients by comparing them with healthy controls. Methods: A sample …
Mannose-binding lectin conjugated to quantum dots as fluorescent nanotools for carbohydrate tracing
CN Lima, WF Oliveira, PMM Silva… - … and Applications in …, 2022 - iopscience.iop.org
Quantum dots (QDs) have stood out as nanotools for glycobiology due to their photostability
and ability to be combined with lectins. Mannose-binding lectin (MBL) is involved in the …
and ability to be combined with lectins. Mannose-binding lectin (MBL) is involved in the …