A 12-year-old Saudi girl, known case of T-cell leukemia with CNS relapse. She was
diagnosed 2 years ago. Multiple cycles of chemotherapy had been used (Fludarabine …

A 13-month-old baby boy with leukaemia experienced a seizure 72 hours after he received
treatment with a methotrexate-containing regimen. On day 1, the boy received treatment with …

Objectives: To establish the incidence and cause of seizures in children diagnosed with
acute lymphoblastic leukemia (ALL) over a 20-year period. Methods: Patients with ALL were …

A girl and a boy with acute lymphoblastic leukaemia developed seizures and
leukodystrophy during treatment with methotrexate [ages, routes, dosages, durations of …

A four years child was diagnosed to have acute lymhoblastic lymphoma (ALL-LI, CALLA+,
WBC count= 92,900/cm) in may 2003 and achieved complete remission following four drug …

A 2-year-old previously healthy girl presented to hospital because of irritability, fatigue,
pallor and lower extremity weakness. Acute lymphoblastic leukemia (non-T non-B type) was …

Discussion Neurological manifestations in patients with leukemia may be due to nervous
system involvement or complications of treatment. Treatment-related neurotoxicity can in …

A 7-year-old male diagnosed case of B-cell acute lymphoblastic leukemia, intermediate risk
group, central nervous system Status 1, received the first dose of methotrexate (2 g/m2) as …

Purpose: Although seizures are relatively common in acute childhood leukemias, evolution
into epilepsy is rare. Methods: We describe three patients with acute leukemias who …

A 16-year-old girl with relapsed T cell acute lymphoblastic leukaemia (ALL) developed
leukoencephalopathy while receiving methotrexate; she developed worsening neurological …